BEST2 rabbit pAb

Applications: WB;IHC;IF
Reactivity: Mouse;Rat
Source: Rabbit
Dilution: WB: 1:500-1000 IHC: 1:200-500
Immunogen: Synthetic Peptide of BEST2
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Observed_band(KD): 50kD
Human_gene_id: 54831
Human_swiss_prot_no: Q8NFU1
Subcellular_location: Cell membrane; Multi-pass membrane protein.
Other_name: Bestrophin-2; Vitelliform macular dystrophy 2-like protein 1
Background: This gene is a member of the bestrophin gene family of anion channels. Bestrophin genes share a similar gene structure with highly conserved exon-intron boundaries, but with distinct 3' ends. Bestrophins are transmembrane proteins that contain a homologous region rich in aromatic residues, including an invariant arg-phe-pro motif. Mutation in one of the family members (bestrophin 1) is associated with vitelliform macular dystrophy. The bestrophin 2 gene is mainly expressed in the retinal pigment epithelium and colon. [provided by RefSeq, Jul 2008],