CK18 rabbit pAb

Applications: WB
Reactivity: Human
Source: Rabbit
Dilution: WB: 1:1000-2000
Immunogen: Recombinant Protein of Keratin type I cytoskeletal 18
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Observed_band(KD): 46kD
Human_gene_id: 3875
Human_swiss_prot_no: P05783
Subcellular_location: Cytoplasm, perinuclear region. Nucleus, nucleolus.
Other_name: KRT18; CYK18; PIG46; Keratin, type I cytoskeletal 18; Cell proliferation-inducing gene 46 protein; Cytokeratin-18; CK-18; Keratin-18; K18
Background: KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008],