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ELK Biotechnology
SKU:ES20731
GRIK2 (GluR6) rabbit pAb
GRIK2 (GluR6) rabbit pAb
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Applications: IHC;IF
Reactivity: Human
Source: Rabbit
Dilution: IHC 1:100-200
Immunogen: Synthetic Peptide of GRIK2 (GluR6) AA range: 119-169
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed_band(KD): 103kD
Human_gene_id: 2898
Human_swiss_prot_no: Q13002
Subcellular_location: Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein.
Other_name: Glutamate receptor, ionotropic kainate 2 (Excitatory amino acid receptor 4;EAA4;Glutamate receptor 6;GluR-6;GluR6)
Background: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing at multiple sites within the first and second transmembrane domains, which is thought to alter the structure and function of the receptor complex. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. Mutations in this gene have been associated with autosomal recessive mental retardation. [provided by RefSeq, Jul 2008],
Reactivity: Human
Source: Rabbit
Dilution: IHC 1:100-200
Immunogen: Synthetic Peptide of GRIK2 (GluR6) AA range: 119-169
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed_band(KD): 103kD
Human_gene_id: 2898
Human_swiss_prot_no: Q13002
Subcellular_location: Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein.
Other_name: Glutamate receptor, ionotropic kainate 2 (Excitatory amino acid receptor 4;EAA4;Glutamate receptor 6;GluR-6;GluR6)
Background: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing at multiple sites within the first and second transmembrane domains, which is thought to alter the structure and function of the receptor complex. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. Mutations in this gene have been associated with autosomal recessive mental retardation. [provided by RefSeq, Jul 2008],
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