HAO1 rabbit pAb

Applications: WB;IHC;IF
Reactivity: Mouse;Rat
Source: Rabbit
Dilution: WB: 1:2000-5000
Immunogen: Recombinant Protein of HAO1
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Observed_band(KD): 41kD
Human_gene_id: 54363
Human_swiss_prot_no: Q9UJM8
Subcellular_location: Peroxisome matrix .
Other_name: Hydroxyacid oxidase 1; HAOX1; Glycolate oxidase; GOX
Background: This gene is one of three related genes that have 2-hydroxyacid oxidase activity yet differ in encoded protein amino acid sequence, tissue expression and substrate preference. Subcellular location of the encoded protein is the peroxisome. Specifically, this gene is expressed primarily in liver and pancreas and the encoded protein is most active on glycolate, a two-carbon substrate. The protein is also active on 2-hydroxy fatty acids. The transcript detected at high levels in pancreas may represent an alternatively spliced form or the use of a multiple near-consensus upstream polyadenylation site. [provided by RefSeq, Jul 2008],