KCNK10 (TREK-2) rabbit pAb

Applications: WB;IHC;IF
Reactivity: Human;Rat;Mouse
Source: Rabbit
Dilution: WB 1:1000-2000, IHC 1:100-200
Immunogen: Synthetic Peptide of KCNK10 (TREK-2) AA range: 16-66
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed_band(KD): 59kD
Human_gene_id: 54207
Human_swiss_prot_no: P57789
Subcellular_location: Membrane ; Multi-pass membrane protein .
Other_name: Potassium channel subfamily K member 10 (Outward rectifying potassium channel protein TREK-2;TREK-2 K(+) channel subunit)
Background: potassium two pore domain channel subfamily K member 10(KCNK10) Homo sapiens The protein encoded by this gene belongs to the family of potassium channel proteins containing two pore-forming P domains. This channel is an open rectifier which primarily passes outward current under physiological K+ concentrations, and is stimulated strongly by arachidonic acid and to a lesser degree by membrane stretching, intracellular acidification, and general anaesthetics. Several alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Sep 2008],