KCNK9 (TASK-3) rabbit pAb

Applications: WB;IHC;IF
Reactivity: Human;Rat;Mouse
Source: Rabbit
Dilution: WB 1:1000-2000, IHC 1:100-200
Immunogen: Synthetic Peptide of KCNK9 (TASK-3) AA range: 220-270
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed_band(KD): 42kD
Human_gene_id: 51305
Human_swiss_prot_no: Q9NPC2
Subcellular_location: Cell membrane ; Multi-pass membrane protein .
Other_name: Potassium channel subfamily K member 9 (Acid-sensitive potassium channel protein TASK-3;TWIK-related acid-sensitive K(+) channel 3;Two pore potassium channel KT3.2;Two pore K(+) channel KT3.2)
Background: This gene encodes a protein that contains multiple transmembrane regions and two pore-forming P domains and functions as a pH-dependent potassium channel. Amplification and overexpression of this gene have been observed in several types of human carcinomas. This gene is imprinted in the brain, with preferential expression from the maternal allele. A mutation in this gene was associated with Birk-Barel mental retardation dysmorphism syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013],