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ELK Biotechnology
SKU:ES20665
MEK-5 rabbit pAb
MEK-5 rabbit pAb
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Applications: WB;IHC;IF
Reactivity: Human;Mouse;Rat
Source: Rabbit
Dilution: WB: 1:1000-2000 IHC: 1:200-500
Immunogen: Recombinant Protein of MEK-5
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Observed_band(KD): 49kD
Human_gene_id: 5067
Human_swiss_prot_no: Q13163
Subcellular_location: nucleus,cytoplasm,spindle,cytosol,
Other_name: MAP2K5; MEK5; MKK5; PRKMK5; Dual specificity mitogen-activated protein kinase kinase 5; MAP kinase kinase 5; MAPKK 5; MAPK/ERK kinase 5; MEK 5
Background: The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been described. [provided by RefSeq, May 2011],
Reactivity: Human;Mouse;Rat
Source: Rabbit
Dilution: WB: 1:1000-2000 IHC: 1:200-500
Immunogen: Recombinant Protein of MEK-5
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Observed_band(KD): 49kD
Human_gene_id: 5067
Human_swiss_prot_no: Q13163
Subcellular_location: nucleus,cytoplasm,spindle,cytosol,
Other_name: MAP2K5; MEK5; MKK5; PRKMK5; Dual specificity mitogen-activated protein kinase kinase 5; MAP kinase kinase 5; MAPKK 5; MAPK/ERK kinase 5; MEK 5
Background: The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been described. [provided by RefSeq, May 2011],
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