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ELK Biotechnology
SKU:ES20578
Histone H2A.X (Phospho Tyr142) rabbit pAb
Histone H2A.X (Phospho Tyr142) rabbit pAb
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Applications: WB
Reactivity: Human;Mouse;Rat
Source: Rabbit
Dilution: WB: 1:1000-2000
Immunogen: Synthetic Peptide of Histone H2A.X (Phospho Tyr142)
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Observed_band(KD): 15kD
Human_gene_id: 3014
Human_swiss_prot_no: P16104
Subcellular_location: Nucleus . Chromosome .
Other_name: H2AFX; H2AX; Histone H2A.x; H2a/x
Background: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. [provided by RefSeq, Oct 2015],
Reactivity: Human;Mouse;Rat
Source: Rabbit
Dilution: WB: 1:1000-2000
Immunogen: Synthetic Peptide of Histone H2A.X (Phospho Tyr142)
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Observed_band(KD): 15kD
Human_gene_id: 3014
Human_swiss_prot_no: P16104
Subcellular_location: Nucleus . Chromosome .
Other_name: H2AFX; H2AX; Histone H2A.x; H2a/x
Background: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. [provided by RefSeq, Oct 2015],
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