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ELK Biotechnology

SKU:ES20438

RFA1 rabbit pAb

RFA1 rabbit pAb

Regular price $250.00 USD
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Size
Applications: WB;ELISA;IHC
Reactivity: Human;Monkey;Mouse;Rat
Source: Rabbit
Dilution: WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Immunogen: Synthesized peptide derived from human RFA1
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Human_gene_id: 6117
Human_swiss_prot_no: P27694
Subcellular_location: Nucleus . Nucleus, PML body . Enriched in PML bodies in cells displaying alternative lengthening of their telomeres. .
Other_name: Replication protein A 70 kDa DNA-binding subunit (RP-A p70;Replication factor A protein 1;RF-A protein 1;Single-stranded DNA-binding protein)
Background: function:It participates in a very early step in initiation. RP-A is a single-stranded DNA-binding protein. Absolutely required for simian virus 40 DNA replication in vitro.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the replication factor A protein 1 family.,subunit:Heterotrimer of 70, 32 and 14 kDa chains. The DNA-binding activity may reside exclusively on the 70 kDa subunit. Interacts with RIP and XPA. Interacts with RPA4.,
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