VCAM-1 rabbit pAb

Applications: WB; ELISA
Reactivity: Human;Rat;Mouse;
Source: Rabbit
Dilution: WB 1:1000-2000 ELISA 1:5000-20000
Immunogen: Synthesized peptide derived from human VCAM-1 AA range: 551-600
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Human_gene_id: 7412
Human_swiss_prot_no: P19320
Subcellular_location: Membrane; Single-pass type I membrane protein.
Other_name: Vascular cell adhesion protein 1 (V-CAM 1;VCAM-1;INCAM-100;CD antigen CD106)
Background: This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Three alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq, Dec 2010],