EKLF (Acetyl Lys274) rabbit pAb

Applications: WB; ELISA
Reactivity: Human;Rat;Mouse;
Source: Rabbit
Dilution: WB 1:1000-2000 ELISA 1:5000-20000
Immunogen: Synthesized peptide derived from human EKLF (Acetyl Lys274)
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed_band(KD): 40kD
Human_gene_id: 10661
Human_swiss_prot_no: Q13351
Subcellular_location: Nucleus . Colocalizes with SUMO1 in nuclear speckles. .
Other_name: Krueppel-like factor 1 (Erythroid krueppel-like transcription factor;EKLF)
Background: This gene encodes a hematopoietic-specific transcription factor that induces high-level expression of adult beta-globin and other erythroid genes. The zinc-finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss-of-function mutations in this gene result in the dominant In(Lu) blood phenotype. [provided by RefSeq, Oct 2009],