Histone H1 (Acetyl Lys66/63/64) rabbit pAb

Applications: WB; ELISA
Reactivity: Human;Mouse;Rat
Source: Rabbit
Dilution: WB 1:1000-2000 ELISA 1:5000-20000
Immunogen: Synthesized peptide derived from human Histone H1 (Acetyl Lys66/63/64)
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed_band(KD): 24kD
Human_gene_id: 3024
Human_swiss_prot_no: Q02539/P16403/P16402/P10412
Subcellular_location: Nucleus . Chromosome . Mainly localizes in euchromatin.
Other_name: Histone H1.1 (Histone H1a)
Background: Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq, Aug 2015],