GGT1 (heavy chain, Cleaved-Gly380) rabbit pAb

Applications: WB; ELISA
Reactivity: Human;Rat;Mouse;
Source: Rabbit
Dilution: WB 1:1000-2000 ELISA 1:5000-20000
Immunogen: Synthesized peptide derived from human GGT1 (heavy chain, Cleaved-Gly380)
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed_band(KD): 46 62kD
Human_gene_id: 2678
Human_swiss_prot_no: P19440
Subcellular_location: Cell membrane ; Single-pass type II membrane protein .
Other_name: Gamma-glutamyltranspeptidase 1 (GGT 1;EC 2.3.2.2;Gamma-glutamyltransferase 1;Glutathione hydrolase 1;EC 3.4.19.13;Leukotriene-C4 hydrolase;EC 3.4.19.14;CD antigen CD224) [Cleaved into: Gamma-glutamyltranspeptidase 1 heavy chain; Gamma-glutamyltranspeptidase 1 light chain]
Background: The enzyme encoded by this gene is a type I gamma-glutamyltransferase that catalyzes the transfer of the glutamyl moiety of glutathione to a variety of amino acids and dipeptide acceptors. The enzyme is composed of a heavy chain and a light chain, which are derived from a single precursor protein. It is expressed in tissues involved in absorption and secretion and may contribute to the etiology of diabetes and other metabolic disorders. Multiple alternatively spliced variants have been identified. There are a number of related genes present on chromosomes 20 and 22, and putative pseudogenes for this gene on chromosomes 2, 13, and 22. [provided by RefSeq, Jan 2014],