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ELK Biotechnology

SKU:ES18432

AHR rabbit pAb

AHR rabbit pAb

Regular price $250.00 USD
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Size
Applications: WB; IF
Reactivity: Human; Mouse;Rat;Fish
Source: Rabbit
Dilution: WB 1:500-2000; IF/ICC 1:100-500
Immunogen: Synthesized peptide derived from human AHR AA range: 408-458
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Human_gene_id: 196
Human_swiss_prot_no: P35869
Subcellular_location: Cytoplasm . Nucleus . Initially cytoplasmic; upon binding with ligand and interaction with a HSP90, it translocates to the nucleus. .
Background: The protein encoded by this gene is a ligand-activated helix-loop-helix transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. This receptor has been shown to regulate xenobiotic-metabolizing enzymes such as cytochrome P450. Before ligand binding, the encoded protein is sequestered in the cytoplasm; upon ligand binding, this protein moves to the nucleus and stimulates transcription of target genes. [provided by RefSeq, Sep 2015],
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