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ELK Biotechnology

SKU:ES18080

BCS1 rabbit pAb

BCS1 rabbit pAb

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Size
Applications: WB
Reactivity: Human; Mouse
Source: Rabbit
Dilution: WB 1:500-2000
Immunogen: Synthesized peptide derived from human BCS1 AA range: 29-79
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Human_gene_id: 617
Human_swiss_prot_no: Q9Y276
Subcellular_location: Mitochondrion inner membrane ; Single-pass membrane protein .
Background: This gene encodes a homolog of the S. cerevisiae bcs1 protein which is involved in the assembly of complex III of the mitochondrial respiratory chain. The encoded protein does not contain a mitochondrial targeting sequence but experimental studies confirm that it is imported into mitochondria. Mutations in this gene are associated with mitochondrial complex III deficiency and the GRACILE syndrome. Several alternatively spliced transcripts encoding two different isoforms have been described. [provided by RefSeq, Jan 2016],
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