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ELK Biotechnology

SKU:ES1772

Blk rabbit pAb

Blk rabbit pAb

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Applications: WB;IHC;IF;ELISA
Reactivity: Human;Mouse;Rat
Source: Rabbit
Dilution: Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human BLK. AA range:456-505
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed_band(KD): 58kD
Human_gene_id: 640
Human_swiss_prot_no: P51451
Subcellular_location: Cell membrane ; Lipid-anchor . Present and active in lipid rafts. Membrane location is required for the phosphorylation of CD79A and CD79B (By similarity). .
Other_name: BLK; Tyrosine-protein kinase Blk; B lymphocyte kinase; p55-Blk
Background: This gene encodes a nonreceptor tyrosine-kinase of the src family of proto-oncogenes that are typically involved in cell proliferation and differentiation. The protein has a role in B-cell receptor signaling and B-cell development. The protein also stimulates insulin synthesis and secretion in response to glucose and enhances the expression of several pancreatic beta-cell transcription factors. [provided by RefSeq, Aug 2010],
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