CE112 rabbit pAb

Applications: WB
Reactivity: Human; Mouse
Source: Rabbit
Dilution: WB 1:500-2000
Immunogen: Synthesized peptide derived from human CE112 AA range: 475-525
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed_band(KD): 105kD
Human_gene_id: 201134
Human_swiss_prot_no: Q8N8E3
Subcellular_location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Localizes around spindle poles in some cells. .
Other_name: Centrosomal protein of 112 kDa (Coiled-coil domain-containing protein 46)
Background: This gene encodes a coiled-coil domain containing protein that belongs to the cell division control protein 42 effector protein family. In neurons, it localizes to the cytoplasm of dendrites and is also enriched in the nucleus where it interacts with the RNA polymerase III transcriptional repressor Maf1 to regulate gamma-aminobutyric acid A receptor surface expression. In addition, the protein has been identified as a component of the human centrosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014],