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ELK Biotechnology
SKU:ES17507
CFC1 rabbit pAb
CFC1 rabbit pAb
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$250.00 USD
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Applications: WB
Reactivity: Human; Mouse
Source: Rabbit
Dilution: WB 1：500-2000
Immunogen: Synthesized peptide derived from human CFC1 AA range: 129-179
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Human_gene_id: 55997
Human_swiss_prot_no: P0CG37
Subcellular_location: Cell membrane ; Lipid-anchor, GPI-anchor . Secreted . Does not exhibit a typical GPI-signal sequence. The C-ter hydrophilic extension of the GPI-signal sequence reduces the efficiency of processing and could lead to the production of an secreted unprocessed form. This extension is found only in primates.
Background: This gene encodes a member of the epidermal growth factor (EGF)- Cripto, Frl-1, and Cryptic (CFC) family, which are involved in signalling during embryonic development. Proteins in this family share a variant EGF-like motif, a conserved cysteine-rich domain, and a C-terminal hydrophobic region. The protein encoded by this gene is necessary for patterning the left-right embryonic axis. Mutations in this gene are associated with defects in organ development, including autosomal visceral heterotaxy and congenital heart disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012],
Reactivity: Human; Mouse
Source: Rabbit
Dilution: WB 1：500-2000
Immunogen: Synthesized peptide derived from human CFC1 AA range: 129-179
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Human_gene_id: 55997
Human_swiss_prot_no: P0CG37
Subcellular_location: Cell membrane ; Lipid-anchor, GPI-anchor . Secreted . Does not exhibit a typical GPI-signal sequence. The C-ter hydrophilic extension of the GPI-signal sequence reduces the efficiency of processing and could lead to the production of an secreted unprocessed form. This extension is found only in primates.
Background: This gene encodes a member of the epidermal growth factor (EGF)- Cripto, Frl-1, and Cryptic (CFC) family, which are involved in signalling during embryonic development. Proteins in this family share a variant EGF-like motif, a conserved cysteine-rich domain, and a C-terminal hydrophobic region. The protein encoded by this gene is necessary for patterning the left-right embryonic axis. Mutations in this gene are associated with defects in organ development, including autosomal visceral heterotaxy and congenital heart disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012],
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