CLD24 rabbit pAb

Applications: WB
Reactivity: Human;Rat;Mouse;
Source: Rabbit
Dilution: WB 1：500-2000
Immunogen: Synthesized peptide derived from human CLD24 AA range: 78-128
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Human_swiss_prot_no: A6NM45
Subcellular_location: Cell junction, tight junction . Cell membrane ; Multi-pass membrane protein .
Background: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. The protein encoded by this gene is 75% identical to the mouse homolog. This gene is upstream of the CLDN22 gene, which overlaps the WWC2 gene on the opposite strand in the genome.[provided by RefSeq, Aug 2010],