DAPK1 (Phospho-Ser308) rabbit pAb

Applications: IHC;IF;WB
Reactivity: Human; Mouse
Source: Rabbit
Dilution: IHC-p 1:50-200, WB 1:500-2000
Immunogen: Synthesized peptide derived from human DAPK1 (Phospho-Ser308)
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed_band(KD): 160kD
Human_gene_id: 1612
Human_swiss_prot_no: P53355
Subcellular_location: [Isoform 1]: Cytoplasm. Cytoplasm, cytoskeleton. Colocalizes with MAP1B in the microtubules and cortical actin fibers.; [Isoform 2]: Cytoplasm. Cytoplasm, cytoskeleton.
Other_name: Death-associated protein kinase 1 (DAP kinase 1;EC 2.7.11.1)
Background: Death-associated protein kinase 1 is a positive mediator of gamma-interferon induced programmed cell death. DAPK1 encodes a structurally unique 160-kD calmodulin dependent serine-threonine kinase that carries 8 ankyrin repeats and 2 putative P-loop consensus sites. It is a tumor suppressor candidate. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013],