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ELK Biotechnology
SKU:ES16941
DISC1 rabbit pAb
DISC1 rabbit pAb
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Applications: WB
Reactivity: Human; Mouse;Rat
Source: Rabbit
Dilution: WB 1：500-2000
Immunogen: Synthesized peptide derived from human DISC1 AA range: 423-473
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Human_gene_id: 27185
Human_swiss_prot_no: Q9NRI5
Subcellular_location: Cytoplasm . Cytoplasm, cytoskeleton . Mitochondrion . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cell junction, synapse, postsynaptic density . Colocalizes with NDEL1 in the perinuclear region and the centrosome (By similarity). Localizes to punctate cytoplasmic foci which overlap in part with mitochondria (PubMed:12506198, PubMed:15797709). Colocalizes with PCNT at the centrosome (PubMed:18955030). .
Background: This gene encodes a protein with multiple coiled coil motifs which is located in the nucleus, cytoplasm and mitochondria. The protein is involved in neurite outgrowth and cortical development through its interaction with other proteins. This gene is disrupted in a t(1;11)(q42.1;q14.3) translocation which segregates with schizophrenia and related psychiatric disorders in a large Scottish family. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008],
Reactivity: Human; Mouse;Rat
Source: Rabbit
Dilution: WB 1：500-2000
Immunogen: Synthesized peptide derived from human DISC1 AA range: 423-473
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Human_gene_id: 27185
Human_swiss_prot_no: Q9NRI5
Subcellular_location: Cytoplasm . Cytoplasm, cytoskeleton . Mitochondrion . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cell junction, synapse, postsynaptic density . Colocalizes with NDEL1 in the perinuclear region and the centrosome (By similarity). Localizes to punctate cytoplasmic foci which overlap in part with mitochondria (PubMed:12506198, PubMed:15797709). Colocalizes with PCNT at the centrosome (PubMed:18955030). .
Background: This gene encodes a protein with multiple coiled coil motifs which is located in the nucleus, cytoplasm and mitochondria. The protein is involved in neurite outgrowth and cortical development through its interaction with other proteins. This gene is disrupted in a t(1;11)(q42.1;q14.3) translocation which segregates with schizophrenia and related psychiatric disorders in a large Scottish family. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008],
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