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ELK Biotechnology
SKU:ES16875
DUX4 rabbit pAb
DUX4 rabbit pAb
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$250.00 USD
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Applications: WB
Reactivity: Human;Rat;Mouse;
Source: Rabbit
Dilution: WB 1：500-2000
Immunogen: Synthesized peptide derived from human DUX4 AA range: 235-285
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Human_swiss_prot_no: Q9UBX2
Subcellular_location: [Isoform 1]: Nucleus . Actively transported through the nuclear pore complex (NPC). .; [Isoform 2]: Nucleus .
Background: This gene is located within a D4Z4 repeat array in the subtelomeric region of chromosome 4q. The D4Z4 repeat is polymorphic in length; a similar D4Z4 repeat array has been identified on chromosome 10. Each D4Z4 repeat unit has an open reading frame (named DUX4) that encodes two homeoboxes; the repeat-array and ORF is conserved in other mammals. The encoded protein has been reported to function as a transcriptional activator of paired-like homeodomain transcription factor 1 (PITX1; GeneID 5307). Contraction of the macrosatellite repeat causes autosomal dominant facioscapulohumeral muscular dystrophy (FSHD). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015],
Reactivity: Human;Rat;Mouse;
Source: Rabbit
Dilution: WB 1：500-2000
Immunogen: Synthesized peptide derived from human DUX4 AA range: 235-285
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Human_swiss_prot_no: Q9UBX2
Subcellular_location: [Isoform 1]: Nucleus . Actively transported through the nuclear pore complex (NPC). .; [Isoform 2]: Nucleus .
Background: This gene is located within a D4Z4 repeat array in the subtelomeric region of chromosome 4q. The D4Z4 repeat is polymorphic in length; a similar D4Z4 repeat array has been identified on chromosome 10. Each D4Z4 repeat unit has an open reading frame (named DUX4) that encodes two homeoboxes; the repeat-array and ORF is conserved in other mammals. The encoded protein has been reported to function as a transcriptional activator of paired-like homeodomain transcription factor 1 (PITX1; GeneID 5307). Contraction of the macrosatellite repeat causes autosomal dominant facioscapulohumeral muscular dystrophy (FSHD). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015],
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