EST3 rabbit pAb

Applications: WB
Reactivity: Human;Rat;Mouse;
Source: Rabbit
Dilution: WB 1:500-2000
Immunogen: Synthesized peptide derived from human EST3 AA range: 447-497
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed_band(KD): 65kD
Human_gene_id: 23491
Human_swiss_prot_no: Q6UWW8
Subcellular_location: Endoplasmic reticulum lumen .
Other_name: Carboxylesterase 3 (EC 3.1.1.1) (Liver carboxylesterase 31 homolog)
Background: This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. This gene is expressed in several tissues, particularly in colon, trachea and in brain, and the protein participates in colon and neural drug metabolism. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported, but the biological validity and/or full-length nature of some variants have not been determined.[provided by RefSeq, Jun 2010],