Ezh2 (phospho-Thr311) rabbit pAb

Applications: WB
Reactivity: Human;Rat;Mouse;
Source: Rabbit
Dilution: WB 1:1000-2000
Immunogen: Synthesized phosho peptide around human Ezh2 (Thr311)
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed_band(KD): 82kD
Human_gene_id: 2146
Human_swiss_prot_no: Q15910
Subcellular_location: Nucleus . Localizes to the inactive X chromosome in trophoblast stem cells. .
Other_name: Histone-lysine N-methyltransferase EZH2 (EC 2.1.1.43) (ENX-1) (Enhancer of zeste homolog 2) (Lysine N-methyltransferase 6)
Background: enhancer of zeste 2 polycomb repressive complex 2 subunit(EZH2) Homo sapiens This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Multiple alternatively splcied transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Feb 2011],