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ELK Biotechnology

SKU:ES16304

FXL18 rabbit pAb

FXL18 rabbit pAb

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Size
Applications: WB
Reactivity: Human;Rat;Mouse;
Source: Rabbit
Dilution: WB 1:500-2000
Immunogen: Synthesized peptide derived from human FXL18 AA range: 7-57
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Human_gene_id: 80028
Human_swiss_prot_no: Q96ME1
Background: The protein encoded by this gene is a member of a family of proteins that contain an approximately 40-amino acid F-box motif. This motif is important for interaction with SKP1 and for targeting some proteins for degradation. The encoded protein has been shown to control the cellular level of FBXL7, a protein that induces mitotic arrest, by targeting it for polyubiquitylation and proteasomal degradation. Members of the F-box protein family, such as FBXL18, are characterized by an approximately 40-amino acid F-box motif. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains. [provided by RefSeq, Mar 2016],
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