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ELK Biotechnology

SKU:ES16189

GGT2 rabbit pAb

GGT2 rabbit pAb

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Size
Applications: WB
Reactivity: Human;Rat;Mouse;
Source: Rabbit
Dilution: WB 1:500-2000
Immunogen: Synthesized peptide derived from human GGT2 AA range: 89-139
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed_band(KD): 60kD
Human_swiss_prot_no: P36268
Subcellular_location: Cytoplasm, perinuclear region . Endoplasmic reticulum . Co-localizes with calnexin in the endoplasmic reticulum.
Other_name: Gamma-glutamyltranspeptidase 2 (GGT 2) (EC 2.3.2.2) (Gamma-glutamyltransferase 2) (Glutathione hydrolase 2) (EC 3.4.19.13) [Cleaved into: Gamma-glutamyltranspeptidase 2 heavy chain; Gamma-glutamyltranspeptidase 2 light chain]
Background: GGT2 belongs to the gamma-glutamyltransferase (GGT; EC 2.3.2.2) gene family. GGT is a membrane-bound extracellular enzyme that cleaves gamma-glutamyl peptide bonds in glutathione and other peptides and transfers the gamma-glutamyl moiety to acceptors. GGT is also key to glutathione homeostasis because it provides substrates for glutathione synthesis (Heisterkamp et al., 2008 [PubMed 18357469]).[supplied by OMIM, Oct 2008],
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