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ELK Biotechnology

SKU:ES15597

HSH2D rabbit pAb

HSH2D rabbit pAb

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Size
Applications: WB
Reactivity: Human; Mouse
Source: Rabbit
Dilution: WB 1:500-2000
Immunogen: Synthesized peptide derived from human HSH2D AA range: 288-338
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed_band(KD): 38kD
Human_gene_id: 84941
Human_swiss_prot_no: Q96JZ2
Subcellular_location: Cytoplasm. Nucleus.
Other_name: Hematopoietic SH2 domain-containing protein (Hematopoietic SH2 protein) (Adaptor in lymphocytes of unknown function X)
Background: T-cell activation requires 2 signals: recognition of antigen by the T-cell receptor (see TCR; MIM 186880) and a costimulatory signal provided primarily by CD28 (MIM 186760) in naive T cells. HSH2 is a target of both of these signaling pathways (Greene et al., 2003 [PubMed 12960172]).[supplied by OMIM, Mar 2008],
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