IRF-7 (phospho-Ser477) rabbit pAb

Applications: WB;IHC
Reactivity: Human;Rat;Mouse;
Source: Rabbit
Dilution: WB 1:500-2000;IHC-p 1:50-300
Immunogen: Synthesized phosho peptide around human IRF-7 (Ser477)
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed_band(KD): 55kD
Human_gene_id: 3665
Human_swiss_prot_no: Q92985
Subcellular_location: Nucleus. Cytoplasm. The phosphorylated and active form accumulates selectively in the nucleus.
Other_name: Interferon regulatory factor 7 (IRF-7)
Background: IRF7 encodes interferon regulatory factor 7, a member of the interferon regulatory transcription factor (IRF) family. IRF7 has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including interferon beta chain genes. Inducible expression of IRF7 is largely restricted to lymphoid tissue. Multiple IRF7 transcript variants have been identified, although the functional consequences of these have not yet been established. [provided by RefSeq, Jul 2008],