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ELK Biotechnology

SKU:ES15396

Jak2 (phospho-Tyr1008) rabbit pAb

Jak2 (phospho-Tyr1008) rabbit pAb

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Size
Applications: WB;ELISA;IHC
Reactivity: Human;Mouse
Source: Rabbit
Dilution: WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Immunogen: Synthesized phosho peptide around human Jak2 (Tyr1008)
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed_band(KD): 130kD
Human_gene_id: 3717
Human_swiss_prot_no: O60674
Subcellular_location: Endomembrane system ; Peripheral membrane protein . Cytoplasm . Nucleus .
Other_name: Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2)
Background: This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis. [provided by RefSeq, Jul 2008],
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