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ELK Biotechnology
SKU:ES15271
KPNA6 rabbit pAb
KPNA6 rabbit pAb
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$250.00 USD
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Applications: WB;IP
Reactivity: Human; Mouse
Source: Rabbit
Dilution: WB 1:500-2000
Immunogen: Synthesized peptide derived from human KPNA6 AA range: 404-454
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed_band(KD): 60kD
Human_gene_id: 23633
Human_swiss_prot_no: O60684
Subcellular_location: nucleus,nuclear pore,nucleoplasm,cytoplasm,cytosol,membrane,
Other_name: Importin subunit alpha-7 (Karyopherin subunit alpha-6)
Background: Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. The protein encoded by this gene is a member of the importin alpha family. [provided by RefSeq, Jul 2008],
Reactivity: Human; Mouse
Source: Rabbit
Dilution: WB 1:500-2000
Immunogen: Synthesized peptide derived from human KPNA6 AA range: 404-454
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed_band(KD): 60kD
Human_gene_id: 23633
Human_swiss_prot_no: O60684
Subcellular_location: nucleus,nuclear pore,nucleoplasm,cytoplasm,cytosol,membrane,
Other_name: Importin subunit alpha-7 (Karyopherin subunit alpha-6)
Background: Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. The protein encoded by this gene is a member of the importin alpha family. [provided by RefSeq, Jul 2008],
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