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ELK Biotechnology
SKU:ES15106
LRP5 rabbit pAb
LRP5 rabbit pAb
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$250.00 USD
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Applications: WB
Reactivity: Human; Mouse
Source: Rabbit
Dilution: WB 1：500-2000
Immunogen: Synthesized peptide derived from human LRP5 AA range: 1047-1097
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Human_gene_id: 4041
Human_swiss_prot_no: O75197
Subcellular_location: Membrane ; Single-pass type I membrane protein . Endoplasmic reticulum . Chaperoned to the plasma membrane by MESD. .
Background: This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014],
Reactivity: Human; Mouse
Source: Rabbit
Dilution: WB 1：500-2000
Immunogen: Synthesized peptide derived from human LRP5 AA range: 1047-1097
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Human_gene_id: 4041
Human_swiss_prot_no: O75197
Subcellular_location: Membrane ; Single-pass type I membrane protein . Endoplasmic reticulum . Chaperoned to the plasma membrane by MESD. .
Background: This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014],
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