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ELK Biotechnology
SKU:ES14533
NDUFA1 Rabbit pAb
NDUFA1 Rabbit pAb
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$250.00 USD
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Applications: IHC; ELISA
Reactivity: Human; Mouse; Rat
Source: Rabbit
Dilution: IHC-p 1:50-200, ELISA(peptide)1:5000-20000
Immunogen: Synthesized peptide derived from human NDUFA1 AA range: 20-100
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Human_gene_id: 4694
Human_swiss_prot_no: O15239
Subcellular_location: Mitochondrion inner membrane ; Single-pass membrane protein ; Matrix side .
Other_name: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 (Complex I-MWFE;CI-MWFE;NADH-ubiquinone oxidoreductase MWFE subunit)
Background: The human NDUFA1 gene codes for an essential component of complex I of the respiratory chain, which transfers electrons from NADH to ubiquinone. It has been noted that the N-terminal hydrophobic domain has the potential to be folded into an alpha-helix spanning the inner mitochondrial membrane with a C-terminal hydrophilic domain interacting with globular subunits of complex I. The highly conserved two-domain structure suggests that this feature is critical for the protein function and might act as an anchor for the NADH:ubiquinone oxidoreductase complex at the inner mitochondrial membrane. However, the NDUFA1 peptide is one of about 31 components of the "hydrophobic protein" (HP) fraction of complex I which is involved in proton translocation. Thus the NDUFA1 peptide may also participate in that function. [provided by RefSeq, Jul 2008],
Reactivity: Human; Mouse; Rat
Source: Rabbit
Dilution: IHC-p 1:50-200, ELISA(peptide)1:5000-20000
Immunogen: Synthesized peptide derived from human NDUFA1 AA range: 20-100
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Human_gene_id: 4694
Human_swiss_prot_no: O15239
Subcellular_location: Mitochondrion inner membrane ; Single-pass membrane protein ; Matrix side .
Other_name: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 (Complex I-MWFE;CI-MWFE;NADH-ubiquinone oxidoreductase MWFE subunit)
Background: The human NDUFA1 gene codes for an essential component of complex I of the respiratory chain, which transfers electrons from NADH to ubiquinone. It has been noted that the N-terminal hydrophobic domain has the potential to be folded into an alpha-helix spanning the inner mitochondrial membrane with a C-terminal hydrophilic domain interacting with globular subunits of complex I. The highly conserved two-domain structure suggests that this feature is critical for the protein function and might act as an anchor for the NADH:ubiquinone oxidoreductase complex at the inner mitochondrial membrane. However, the NDUFA1 peptide is one of about 31 components of the "hydrophobic protein" (HP) fraction of complex I which is involved in proton translocation. Thus the NDUFA1 peptide may also participate in that function. [provided by RefSeq, Jul 2008],
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