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ELK Biotechnology

SKU:ES14462

NPC2 rabbit pAb

NPC2 rabbit pAb

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Size
Applications: WB
Reactivity: Human; Mouse
Source: Rabbit
Dilution: WB 1:500-2000
Immunogen: Synthesized peptide derived from human NPC2 AA range: 9-59
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Human_gene_id: 10577
Human_swiss_prot_no: P61916
Subcellular_location: Secreted . Endoplasmic reticulum . Lysosome . Interaction with cell-surface M6PR mediates endocytosis and targeting to lysosomes. .
Background: This gene encodes a protein containing a lipid recognition domain. The encoded protein may function in regulating the transport of cholesterol through the late endosomal/lysosomal system. Mutations in this gene have been associated with Niemann-Pick disease, type C2 and frontal lobe atrophy. [provided by RefSeq, Jul 2008],
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