OCT1 Monoclonal Rabbit pAb

Applications: IHC;IF;WB
Reactivity: Human;Rat;Mouse;
Source: Rabbit
Dilution: IHC-p 1:50-200, WB 1:500-2000
Immunogen: Synthesized peptide derived from human OCT1 Monoclonal Antibody
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed_band(KD): 61kD
Human_gene_id: 6580
Human_swiss_prot_no: O15245
Subcellular_location: Basolateral cell membrane ; Multi-pass membrane protein .
Other_name: Solute carrier family 22 member 1 (Organic cation transporter 1;hOCT1)
Background: Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein. Two transcript variants encoding two different isoforms have been found for this gene, but only the longer variant encodes a functional transporter. [provided by RefSeq, Jul 2008],