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ELK Biotechnology
SKU:ES14357
OTOG rabbit pAb
OTOG rabbit pAb
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$250.00 USD
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Applications: IHC;IF
Reactivity: Human; Mouse
Source: Rabbit
Dilution: IHC-p 1：50-200
Immunogen: Synthesized peptide derived from human OTOG AA range: 2706-2756
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Human_gene_id: 340990
Human_swiss_prot_no: Q6ZRI0
Subcellular_location: Apical cell membrane ; Peripheral membrane protein ; Extracellular side . Secreted, extracellular space . Found in fiber-like structures during the maturation process of the tectorial membrane. .
Background: The protein encoded by this gene is a component of the acellular membranes of the inner ear. Disruption of the orthologous mouse gene shows that it plays a role in auditory and vestibular functions. It is involved in fibrillar network organization, the anchoring of otoconial membranes and cupulae to the neuroepithelia, and likely in sound stimulation resistance. Mutations in this gene cause autosomal recessive nonsyndromic deafness, type 18B. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2014],
Reactivity: Human; Mouse
Source: Rabbit
Dilution: IHC-p 1：50-200
Immunogen: Synthesized peptide derived from human OTOG AA range: 2706-2756
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Human_gene_id: 340990
Human_swiss_prot_no: Q6ZRI0
Subcellular_location: Apical cell membrane ; Peripheral membrane protein ; Extracellular side . Secreted, extracellular space . Found in fiber-like structures during the maturation process of the tectorial membrane. .
Background: The protein encoded by this gene is a component of the acellular membranes of the inner ear. Disruption of the orthologous mouse gene shows that it plays a role in auditory and vestibular functions. It is involved in fibrillar network organization, the anchoring of otoconial membranes and cupulae to the neuroepithelia, and likely in sound stimulation resistance. Mutations in this gene cause autosomal recessive nonsyndromic deafness, type 18B. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2014],
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