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ELK Biotechnology

SKU:ES14187

PDE4B rabbit pAb

PDE4B rabbit pAb

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Size
Applications: WB
Reactivity: Human;Rat
Source: Rabbit
Dilution: WB 1:500-2000
Immunogen: Synthesized peptide derived from human PDE4B AA range: 103-153
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Human_gene_id: 5142
Human_swiss_prot_no: Q07343
Subcellular_location: [Isoform PDE4B5]: Cytoplasm . Cell membrane .
Background: This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. The encoded protein regulates the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014],
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