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ELK Biotechnology
SKU:ES14175
PDLI3 rabbit pAb
PDLI3 rabbit pAb
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$250.00 USD
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Applications: WB;IHC
Reactivity: Human; Mouse;Rat
Source: Rabbit
Dilution: WB 1:500-2000;IHC-p 1:50-300
Immunogen: Synthesized peptide derived from human PDLI3 AA range: 251-301
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Human_gene_id: 27295
Human_swiss_prot_no: Q53GG5
Subcellular_location: Cytoplasm, myofibril, sarcomere, Z line . Localizes to myofiber Z-lines.
Background: The protein encoded by this gene contains a PDZ domain and a LIM domain, indicating that it may be involved in cytoskeletal assembly. In support of this, the encoded protein has been shown to bind the spectrin-like repeats of alpha-actinin-2 and to colocalize with alpha-actinin-2 at the Z lines of skeletal muscle. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Aberrant alternative splicing of this gene may play a role in myotonic dystrophy. [provided by RefSeq, Apr 2012],
Reactivity: Human; Mouse;Rat
Source: Rabbit
Dilution: WB 1:500-2000;IHC-p 1:50-300
Immunogen: Synthesized peptide derived from human PDLI3 AA range: 251-301
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Human_gene_id: 27295
Human_swiss_prot_no: Q53GG5
Subcellular_location: Cytoplasm, myofibril, sarcomere, Z line . Localizes to myofiber Z-lines.
Background: The protein encoded by this gene contains a PDZ domain and a LIM domain, indicating that it may be involved in cytoskeletal assembly. In support of this, the encoded protein has been shown to bind the spectrin-like repeats of alpha-actinin-2 and to colocalize with alpha-actinin-2 at the Z lines of skeletal muscle. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Aberrant alternative splicing of this gene may play a role in myotonic dystrophy. [provided by RefSeq, Apr 2012],
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