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ELK Biotechnology

SKU:ES14032

POLD4 Rabbit pAb

POLD4 Rabbit pAb

Regular price $250.00 USD
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Size
Applications: WB;IHC;IF;ELISA
Reactivity: Human;Rat;Mouse;
Source: Rabbit
Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
Immunogen: Synthesized peptide derived from human POLD4 AA range: 43-93
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Human_gene_id: 57804
Human_swiss_prot_no: Q9HCU8
Subcellular_location: Nucleus . Partially recruited to DNA damage sites within 2 hours following UV irradiation, before degradation. .
Other_name: DNA polymerase delta subunit 4 (DNA polymerase delta subunit p12)
Background: This gene encodes the smallest subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. The encoded protein enhances the activity of DNA polymerase delta and plays a role in fork repair and stabilization through interactions with the DNA helicase Bloom syndrome protein. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012],
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