SAMHD1 (phospho-Thr592) rabbit pAb

Applications: WB
Reactivity: Human;Mouse;Rat
Source: Rabbit
Dilution: WB 1:1000-2000
Immunogen: Synthesized phosho peptide around human SAMHD1 (Thr592)
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed_band(KD): 72kD
Human_gene_id: 25939
Human_swiss_prot_no: Q9Y3Z3
Subcellular_location: Nucleus . Chromosome . Localizes to sites of DNA double-strand breaks in response to DNA damage. .
Other_name: SAM domain and HD domain-containing protein 1 (EC 3.1.4.-) (Dendritic cell-derived IFNG-induced protein) (DCIP) (Monocyte protein 5) (MOP-5)
Background: SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1(SAMHD1) Homo sapiens This gene may play a role in regulation of the innate immune response. The encoded protein is upregulated in response to viral infection and may be involved in mediation of tumor necrosis factor-alpha proinflammatory responses. Mutations in this gene have been associated with Aicardi-Goutieres syndrome. [provided by RefSeq, Mar 2010],