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ELK Biotechnology

SKU:ES13170

SEC61B Rabbit pAb

SEC61B Rabbit pAb

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Size
Applications: IHC; ELISA
Reactivity: Human; Mouse; Rat
Source: Rabbit
Dilution: IHC-p 1:50-200, ELISA(peptide)1:5000-20000
Immunogen: Synthesized peptide derived from human SEC61B AA range: 30-110
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Human_gene_id: 10952
Human_swiss_prot_no: P60468
Subcellular_location: Endoplasmic reticulum membrane ; Single-pass membrane protein .
Other_name: Protein transport protein Sec61 subunit beta
Background: The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. Oligomers of the Sec61 complex form a transmembrane channel where proteins are translocated across and integrated into the ER membrane. This complex consists of three membrane proteins- alpha, beta, and gamma. This gene encodes the beta-subunit protein. The Sec61 subunits are also observed in the post-ER compartment, suggesting that these proteins can escape the ER and recycle back. There is evidence for multiple polyadenylated sites for this transcript. [provided by RefSeq, Jul 2008],
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