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ELK Biotechnology

SKU:ES13112

SIA4A rabbit pAb

SIA4A rabbit pAb

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Applications: WB;ELISA;IHC
Reactivity: Human; Mouse
Source: Rabbit
Dilution: WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Immunogen: Synthesized peptide derived from human SIA4A AA range: 189-239
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Human_gene_id: 6482
Human_swiss_prot_no: Q11201
Subcellular_location: Golgi apparatus, Golgi stack membrane ; Single-pass type II membrane protein . Golgi apparatus, trans-Golgi network membrane ; Single-pass type II membrane protein . Secreted. Membrane-bound form in medial and trans cisternae of Golgi (PubMed:9182658). Secreted into the body fluid. .
Background: The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The encoded protein is normally found in the Golgi but can be proteolytically processed to a soluble form. Correct glycosylation of the encoded protein may be critical to its sialyltransferase activity. This protein, which is a member of glycosyltransferase family 29, can use the same acceptor substrates as does sialyltransferase 4B. Two transcript variants encoding the same protein have been found for this gene. Other transcript variants may exist, but have not been fully characterized yet. [provided by RefSeq, Jul 2008],
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