SPRE2 rabbit pAb

Applications: WB;IHC
Reactivity: Human; Mouse;Rat
Source: Rabbit
Dilution: WB 1:500-2000;IHC-p 1:50-300
Immunogen: Synthesized peptide derived from human SPRE2 AA range: 68-118
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Human_gene_id: 200734
Human_swiss_prot_no: Q7Z698
Subcellular_location: Cell membrane ; Peripheral membrane protein ; Cytoplasmic side . Cytoplasmic vesicle, secretory vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Cytoplasm . Detected in the cytoplasm of the stratum spinosum cells, where it is associated with cytoplasmic vesicles that are supposed to be secretory granules. .
Background: SPRED2 is a member of the Sprouty (see SPRY1; MIM 602465)/SPRED family of proteins that regulate growth factor-induced activation of the MAP kinase cascade (see MAPK1; MIM 176948) (Nonami et al., 2004 [PubMed 15465815]).[supplied by OMIM, Mar 2008],