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ELK Biotechnology

SKU:ES12954

SRGP2 rabbit pAb

SRGP2 rabbit pAb

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Size
Applications: WB
Reactivity: Human; Mouse;Rat
Source: Rabbit
Dilution: WB 1:500-2000
Immunogen: Synthesized peptide derived from human SRGP2 AA range: 476-526
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Human_gene_id: 23380
Human_swiss_prot_no: O75044
Subcellular_location: Cell membrane . Cell projection, dendritic spine . Cell junction, synapse, postsynaptic density . Cell junction, synapse, postsynaptic cell membrane . Cell projection, lamellipodium . Cytoplasmic vesicle, phagosome . Nucleus . Cytoplasm, cytosol . Recruited to actin-rich phagosomes during phagocytosis (By similarity). Translocates from nucleus to cytoplasm during development (By similarity). .
Background: This locus encodes a member of the SLIT-ROBO Rho GTPase activating protein family. The encoded protein stimulates GTPase activity of Rac1, and plays a role in cortical neuron development. This locus has several paralogs on human chromosome 1 resulting from segmental duplication. While this locus itself is conserved among various species, the paralogs are found only in the genus Homo, and not in the genomes of non-human great apes. Alternatively spliced transcript variants have been described for this locus. [provided by RefSeq, Jul 2014],
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