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ELK Biotechnology

SKU:ES11125

TLN2 rabbit pAb

TLN2 rabbit pAb

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Size
Applications: IHC;IF
Reactivity: Human;Mouse
Source: Rabbit
Dilution: IHC-p 1:50-300
Immunogen: Synthesized peptide derived from part region of human protein
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed_band(KD): 279kD
Human_gene_id: 83660
Human_swiss_prot_no: Q9Y4G6
Subcellular_location: Cytoplasm . Cell junction, focal adhesion . Cell junction, synapse . Cell membrane; Peripheral membrane protein; Cytoplasmic side . Cytoplasm, cytoskeleton . Focal adhesion plaques and synapses (PubMed:12422219). .
Background: This gene encodes a protein related to talin 1, a cytoskeletal protein that plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. This protein has a different pattern of expression compared to talin 1 but, like talin 1, is thought to associate with unique transmembrane receptors to form novel linkages between extracellular matrices and the actin cytoskeleton. [provided by RefSeq, Jul 2008],
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