FLRT1 rabbit pAb

Applications: WB;ELISA
Reactivity: Human;Rat;Mouse;
Source: Rabbit
Dilution: WB 1:500-2000 ELISA 1:5000-20000
Immunogen: Synthesized peptide derived from part region of human protein
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed_band(KD): 71kD
Human_gene_id: 23769
Human_swiss_prot_no: Q9NZU1
Subcellular_location: Cell membrane ; Single-pass membrane protein . Endoplasmic reticulum membrane . Cytoplasmic vesicle membrane . Cytoplasm, perinuclear region . Cell junction, focal adhesion . Secreted . Cell projection, neuron projection . Cell junction . In addition to its location at the cell membrane, colocalizes with FGFR1 in punctate perinuclear cytoplasmic vesicles. Detected along neurites and at contacts between neurite termini and other cells. Proteolytic cleavage gives rise to a shedded ectodomain. .
Background: fibronectin leucine rich transmembrane protein 1(FLRT1) Homo sapiens This gene encodes a member of the fibronectin leucine rich transmembrane protein (FLRT) family. The family members may function in cell adhesion and/or receptor signalling. Their protein structures resemble small leucine-rich proteoglycans found in the extracellular matrix. The encoded protein shares sequence similarity with two other family members, FLRT2 and FLRT3. This gene is expressed in kidney and brain. [provided by RefSeq, Jul 2008],