VASN rabbit pAb

Applications: WB;ELISA
Reactivity: Human;Mouse
Source: Rabbit
Dilution: WB 1:500-2000 ELISA 1:5000-20000
Immunogen: Synthesized peptide derived from part region of human protein
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed_band(KD): 74kD
Human_gene_id: 114990
Human_swiss_prot_no: Q6EMK4
Subcellular_location: Membrane ; Single-pass type I membrane protein . Secreted .
Background: function:May act as an inhibitor of TGF-beta signaling.,PTM:N-glycosylated.,similarity:Contains 1 EGF-like domain.,similarity:Contains 1 fibronectin type-III domain.,similarity:Contains 11 LRR (leucine-rich) repeats.,subunit:Interacts with TGFB1, TGFB2 and TGFB3.,tissue specificity:Expressed at highest levels in aorta, at intermediate levels in kidney and placenta and at lowest levels in brain, heart, liver, lung and skeletal muscle. Within the aorta, the strongest expression is found in the tunica media of the proximal ascending aorta, the descending thoracic aorta, the abdominal aorta and the coronary arteries. Within the kidney, expression is found in the interstitial cells.,