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ELK Biotechnology

SKU:ES10984

VWF rabbit pAb

VWF rabbit pAb

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Size
Applications: IHC;IF
Reactivity: Human;Rat;Mouse
Source: Rabbit
Dilution: IHC-p 1:50-300
Immunogen: Synthesized peptide derived from part region of human protein AA range: 911-960
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed_band(KD): 309kD
Human_gene_id: 7450
Human_swiss_prot_no: P04275
Subcellular_location: Secreted . Secreted, extracellular space, extracellular matrix . Localized to storage granules.
Background: This gene encodes a glycoprotein involved in hemostasis. The encoded preproprotein is proteolytically processed following assembly into large multimeric complexes. These complexes function in the adhesion of platelets to sites of vascular injury and the transport of various proteins in the blood. Mutations in this gene result in von Willebrand disease, an inherited bleeding disorder. An unprocessed pseudogene has been found on chromosome 22. [provided by RefSeq, Oct 2015],
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