ELK Biotechnology

SKU:ES10701

I17RD rabbit pAb

I17RD rabbit pAb

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Size
Applications: WB;ELISA
Reactivity: Human;Mouse
Source: Rabbit
Dilution: WB 1:500-2000 ELISA 1:5000-20000
Immunogen: Synthesized peptide derived from part region of human protein
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed_band(KD): 81kD
Human_gene_id: 54756
Human_swiss_prot_no: Q8NFM7
Subcellular_location: Golgi apparatus membrane ; Single-pass type I membrane protein . Cell membrane ; Single-pass type I membrane protein . Predominantly associated with the Golgi apparatus and is partially translocated to the plasma membrane upon stimulation.; [Isoform 4]: Cytoplasm.
Background: This gene encodes a membrane protein belonging to the interleukin-17 receptor (IL-17R) protein family. The encoded protein is a component of the interleukin-17 receptor signaling complex, and the interaction between this protein and IL-17R does not require the interleukin. The gene product also affects fibroblast growth factor signaling, inhibiting or stimulating growth through MAPK/ERK signaling. Alternate splicing generates multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jan 2016],
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