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ELK Biotechnology

SKU:ES10475

CAC1G rabbit pAb

CAC1G rabbit pAb

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Size
Applications: IHC;IF
Reactivity: Human;Rat
Source: Rabbit
Dilution: IHC-p 1:50-300
Immunogen: Synthesized peptide derived from human protein . at AA range: 360-440
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed_band(KD): 261kD
Human_gene_id: 8913
Human_swiss_prot_no: O43497
Subcellular_location: Cell membrane ; Multi-pass membrane protein . Cytoplasm .
Background: calcium voltage-gated channel subunit alpha1 G(CACNA1G) Homo sapiens Voltage-sensitive calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division, and cell death. This gene encodes a T-type, low-voltage activated calcium channel. The T-type channels generate currents that are both transient, owing to fast inactivation, and tiny, owing to small conductance. T-type channels are thought to be involved in pacemaker activity, low-threshold calcium spikes, neuronal oscillations and resonance, and rebound burst firing. Many alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Sep 2011],
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