CAC1E rabbit pAb

Applications: IHC;IF
Reactivity: Human;Mouse;Rat
Source: Rabbit
Dilution: IHC-p 1:50-300
Immunogen: Synthesized peptide derived from human protein . at AA range: 370-450
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed_band(KD): 254kD
Human_gene_id: 777
Human_swiss_prot_no: Q15878
Subcellular_location: Membrane; Multi-pass membrane protein.
Background: calcium voltage-gated channel subunit alpha1 E(CACNA1E) Homo sapiens Voltage-dependent calcium channels are multisubunit complexes consisting of alpha-1, alpha-2, beta, and delta subunits in a 1:1:1:1 ratio. These channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This gene encodes the alpha-1E subunit of the R-type calcium channels, which belong to the 'high-voltage activated' group that maybe involved in the modulation of firing patterns of neurons important for information processing. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Apr 2011],